Denali Therapeutics Inc. (DNLI)
Healthcare › Biological Products, (No Diagnostic Substances)
Price History
Feb 9, 2026 — Apr 4, 2026Investment Snapshot
- P/B of 3.09 — trading above book value
- Piotroski F-Score 2/9 — signs of financial weakness
- Loss-making — negative ROE of -48.5%
- Revenue declining 100% annually
Denali Therapeutics Inc. (DNLI) is a Healthcare company operating in Biological Products, (No Diagnostic Substances), listed on the NASDAQ , with a market capitalisation of $3.1 billion . Key value metrics: P/B ratio 3.09, Piotroski F-Score 2 out of 9 .
Value Score
Key Metrics
Current vs 5-Year Average
Based on 5 years of SEC filingsRevenue & Net Income
Financial Statements
| Metric | FY22 | FY23 | FY24 |
|---|---|---|---|
| Revenue | $X.XB | $X.XB | $X.XB |
| Gross Profit | $X.XB | $X.XB | $X.XB |
| Operating Income | $X.XB | $X.XB | $X.XB |
| Net Income | $X.XB | $X.XB | $X.XB |
| EBITDA | $X.XB | $X.XB | $X.XB |
| Total Assets | $X.XB | $X.XB | $X.XB |
| Total Liabilities | $X.XB | $X.XB | $X.XB |
Denali Therapeutics Inc. — Fundamental Analysis Summary
On financial health, DNLI shows a weak Piotroski F-Score of 2/9, a signal of deteriorating financial health, and negative return on equity of -48.5% (sector average: -19.8%), and minimal leverage with a debt-to-equity ratio of 0.13.
StockPik's composite Value Score for DNLI is 35/100 — reflecting current market or financial concerns. The score is built from ten fundamental signals: P/E, P/B, PEG ratio, P/S ratio, return on equity, gross margin, debt-to-equity, current ratio, dividend yield, and Piotroski F-Score.
DNLI shows revenue declining at 100% year-over-year, with earnings declining at 21%.